The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

Feb. 24, 2011
Applicants:

Eric Connor, Los Gatos, CA (US);

Kalpesh Biyani, Newark, CA (US);

Scott Hecker, Del Mar, CA (US);

Inez Lees, Mountain View, CA (US);

Paul Mansky, San Francisco, CA (US);

Yongqi Mu, Los Altos, CA (US);

Faleh Salaymeh, Sunnyvale, CA (US);

Hongmin Zhang, Fremont, CA (US);

David Bergbreiter, College Station, TX (US);

Grace Huynh, San Francisco, CA (US);

Michael James Cope, Berkeley, CA (US);

Elizabeth Goka, San Jose, CA (US);

Angela Lee, San Jose, CA (US);

Deidre Madsen, Sunnyvale, CA (US);

Jun Shao, Fremont, CA (US);

Xinnan Zhang, Campbell, CA (US);

Inventors:

Eric Connor, Los Gatos, CA (US);

Kalpesh Biyani, Newark, CA (US);

Scott Hecker, Del Mar, CA (US);

Inez Lees, Mountain View, CA (US);

Paul Mansky, San Francisco, CA (US);

YongQi Mu, Los Altos, CA (US);

Faleh Salaymeh, Sunnyvale, CA (US);

Hongmin Zhang, Fremont, CA (US);

David Bergbreiter, College Station, TX (US);

Grace Huynh, San Francisco, CA (US);

Michael James Cope, Berkeley, CA (US);

Elizabeth Goka, San Jose, CA (US);

Angela Lee, San Jose, CA (US);

Deidre Madsen, Sunnyvale, CA (US);

Jun Shao, Fremont, CA (US);

Xinnan Zhang, Campbell, CA (US);

Assignee:

Relypsa, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/785 (2006.01); C08G 73/02 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/785 (2013.01); A61K 45/06 (2013.01); C08G 73/02 (2013.01); C08G 73/0206 (2013.01);
Abstract

The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.


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