The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2017
Filed:
Jan. 14, 2013
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4355 (2006.01); A61K 31/436 (2006.01); A61K 31/439 (2006.01); A61K 31/44 (2006.01); A61K 31/517 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); A61K 31/438 (2006.01); A61K 31/4402 (2006.01); A61K 31/4433 (2006.01); A61K 31/52 (2006.01); G01N 33/53 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61K 31/436 (2013.01); A61K 31/438 (2013.01); A61K 31/439 (2013.01); A61K 31/4355 (2013.01); A61K 31/44 (2013.01); A61K 31/4402 (2013.01); A61K 31/4433 (2013.01); A61K 31/517 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); G01N 33/53 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); G01N 2440/14 (2013.01); G01N 2500/04 (2013.01);
Abstract
Methods and composition for tumor therapy, especially esophageal adenocarcinoma (EAC), are described. For example, in certain aspects methods for determining Hedgehog and mTOR signaling pathway status to select patients for administering a combination therapy of Hedgehog and mTOR signaling inhibitors are described. Furthermore, the invention provides compositions that involve testing kits for determining signaling status.