The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

Aug. 04, 2015
Applicants:

Ventirx Pharmaceuticals, Inc., Seattle, WA (US);

Array Biopharma, Inc., Boulder, CO (US);

Inventors:

James Jeffry Howbert, Redmond, WA (US);

Gregory Dietsch, Snohomish, WA (US);

Robert Hershberg, Seattle, WA (US);

Laurence E. Burgess, Boulder, CO (US);

Joseph P. Lyssikatos, Piedmont, CA (US);

Brad Newhouse, Boulder, CO (US);

Hong-Woon Yang, Potomac, MD (US);

Assignees:

VENTIRX PHARMACEUTICALS, INC., Seattle, WA (US);

ARRAY BIOPHARMA, INC., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A61K 31/55 (2006.01); C07D 223/14 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 223/16 (2006.01); C07D 401/04 (2006.01); C07D 405/04 (2006.01); C07D 405/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/55 (2013.01); C07D 223/14 (2013.01); C07D 223/16 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 405/04 (2013.01); C07D 405/10 (2013.01);
Abstract

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-versus-host disease.


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