The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

Nov. 07, 2012
Applicant:

Rheinisch-westfälische Technische Hochschule Aachen, Aachen, DE;

Inventors:

Wilhelm Jahnen-Dechent, Aachen, DE;

Andreas Pasch, Bern, CH;

Stefan Farese, Solothum, CH;

Steffen Gräber, Kerkrade, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/84 (2006.01); G01N 21/51 (2006.01); G01N 33/48 (2006.01); G01N 21/47 (2006.01);
U.S. Cl.
CPC ...
G01N 33/84 (2013.01); G01N 21/51 (2013.01); G01N 33/48 (2013.01); G01N 2021/4707 (2013.01); G01N 2800/107 (2013.01); G01N 2800/323 (2013.01);
Abstract

The present invention relates to a method for determining the propensity of a fluid for calcification characterized by the following steps: (i) adding a soluble calcium salt and a soluble phosphate salt to a sample of the fluid; (ii) incubating the sample at conditions allowing the formation of calciprotein particles (CPPs); and (iii) determining one or more of the following: (a) the rate of the formation of primary and/or secondary CPPs; (b) the amount of primary and/or secondary CPPs; and/or (c) the rate of the transition of primary CPPs into secondary CPPs, wherein an increase in one or more of (a), (b) and/or (c) of step (iii) indicates an increased propensity of the fluid for calcification.


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