The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2017
Filed:
Oct. 08, 2009
Applicants:
Dorothee Von Laer, Innsbruck, AT;
Tsanan Heimann, Mainz, DE;
Inventors:
Dorothee Von Laer, Innsbruck, AT;
Tsanan Heimann, Mainz, DE;
Assignee:
VIRATHERAPEUTICS GMBH, Innsbruck, AT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); C12N 15/86 (2006.01); C12N 13/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 2760/10122 (2013.01); C12N 2760/20243 (2013.01); C12N 2760/20245 (2013.01); C12N 2810/6072 (2013.01);
Abstract
The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV, to virus producing cells which produce LCMV-GP-pseudotyped VSV virions, and to the use of said vectors and cells in the therapy of solid tumors, especially brain tumors.