The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

Dec. 27, 2013
Applicant:

Immunomax Co., Ltd., Seoul, KR;

Inventors:

Se-Ho Park, Seoul, KR;

Eunbi Yi, Seoul, KR;

Assignee:

IMMUNOMAX CO., LTD., Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); C12N 7/00 (2006.01); C12N 5/071 (2010.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C12N 5/0686 (2013.01); C12N 15/102 (2013.01); C12N 2510/00 (2013.01); C12N 2510/02 (2013.01); C12N 2710/16634 (2013.01); C12N 2710/16651 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16151 (2013.01);
Abstract

The present invention relates to a cell line having an increased ability to produce virus and a method for preparing thereof, and more particularly, to a cell line that has an increased ability to produce virus, due to the loss of the function of the Bst-2 (tetherin) gene, and to a production method thereof. According to the present invention, a cell line lacking the function of the Bst-2 gene has an excellent ability to produce virus, compared to a wild-type cell line. Thus, when the mutant cell line is used as a virus-producing cell line, the production yield of virus can be increased. In addition, the mutant cell line can be used for the production and research of vaccines for preventing and treating viral diseases.


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