The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2017
Filed:
Feb. 09, 2015
Applicant:
University of Maryland, Baltimore County, Baltimore, MD (US);
Inventor:
Suzanne Ostrand-Rosenberg, Columbia, MD (US);
Assignee:
UNIVERSITY OF MARYLAND, BALTIMORE COUNTY, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70532 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention provides for a therapeutic cancer treatment using a soluble CD80 fusion protein that binds to PDL1 and inhibits PDL1-PD1 interactions thereby overcoming PDL1-induced immune suppression and restoring T cell activation.