The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

May. 01, 2015
Applicant:

Curonz Holdings Company Limited, Wellsford, NZ;

Inventors:

Paul William Richard Harris, Waitakere, NZ;

Margaret Anne Brimble, Auckland, NZ;

Frank Sieg, Wellsford, NZ;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); C07K 16/00 (2006.01); C07K 5/00 (2006.01); C07K 7/08 (2006.01); C07K 14/48 (2006.01); C07K 7/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C07K 7/06 (2013.01); C07K 14/48 (2013.01); A61K 38/00 (2013.01); G01N 2800/28 (2013.01); G01N 2800/285 (2013.01); G01N 2800/2835 (2013.01); G01N 2800/2878 (2013.01); G01N 2800/2892 (2013.01);
Abstract

Embodiments of this invention include synthetic compounds (NRP analogs) of peptides termed neural regeneration peptides (NRPs). NRP analogs are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizing β-turns, acetylation of terminal glycine residues or by cyclization. NRP analogs can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.


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