The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2017
Filed:
Mar. 19, 2014
Shanghai Institute of Pharmaceutical Industry, Shanghai, CN;
China State Institute of Pharmaceutical Industry, Shanghai, CN;
Baoquan Zhu, Shanghai, CN;
Yongzhi Shu, Shanghai, CN;
Jun Lin, Shanghai, CN;
Haifeng Hu, Shanghai, CN;
Quanhai Liu, Shanghai, CN;
Bin Zhou, Shanghai, CN;
SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, Shanghai, CN;
CHINA STATE INSTITUTE OF PHARMACEUTICAL INDUSTRY, Shnaghai, CN;
Abstract
Disclosed are a platinum (II) compound, a preparation method therefor, and a pharmaceutical composition and an application thereof. The preparation method comprises the following steps: enabling dihydrate diammine platinum nitrate (4) to react with the carboxylate ligand derivative (5) in water, to produce a platinum (II) compound. Also provided are an application of the platinum (II) compound in preparation of an antitumor drug, and a pharmaceutical composition. The pharmaceutical composition contains an active component and a medicinal carrier, the active component containing the platinum (II) compound, and the mass percentage of the active component being 0.1%-95%. The platinum (II) compound of the present invention is well water-soluble, low toxic, easily prepared, and efficient in antitumor activity.