The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2017
Filed:
Feb. 16, 2015
Jiangsu Nhwaluokang Pharmceutical Research and Development Co., Ltd, Xuzhou, Jiangsu, CN;
Qingeng Li, Chongqing, CN;
Tao Wang, Chongqing, CN;
Gang Chen, Chongqing, CN;
Yuanzhong Wang, Chongqing, CN;
Wei Mao, Chongqing, CN;
Lingguo Zeng, Chongqing, CN;
Tong Wu, Chongqing, CN;
Dahai Chen, Chongqing, CN;
Abstract
The present invention discloses a class of water soluble taxane derivatives, a method for treating tumor using the same, use thereof as anti-tumor drugs and use thereof in the preparation of anti-tumor drugs. The water soluble taxane derivatives have the general formula (I-1), (I-2) or (I-3): wherein, Ris H or methyl; Ris H, methyl or acetyl; Ris phenyl or OC(CH); X is H, Calkyl or F; Y is F or Calkyl substituted with one or more F; n is 1, 2, 3, 4, 5 or 6; W is NRR.A or Rand Rare each independently H, Calkyl optionally substituted with phenyl, or Ccycloalkyl; m is 0, 1, 2 or 3; and A is a pharmaceutically acceptable acid.