The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2017
Filed:
Aug. 13, 2014
Applicant:
Medivir Ab, Huddinge, SE;
Inventors:
Urszula Grabowska, Essex, GB;
Lourdes Salvador Oden, Huddinge, SE;
Victor M. Diaz Perez, Cambridge, GB;
Andrew Carr, Cambridge, GB;
Assignee:
MEDIVIR AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/048 (2006.01); A61K 31/496 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 491/048 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01); C07B 2200/13 (2013.01);
Abstract
There is provided Form 2 crystalline polymorph consisting of N-[1-6-(ethynyl-3-oxo-hexahydro-furo[3,2-b]pyrrole-4-carbonyl)-3-methyl-butyl]-4-[5-fluoro-2-(4-methyl-piperazin-1-yl)thiazol-4-yl]-benzamide monohydrochloride and N-[1-6-(ethynyl-3-oxo-hexahydro-furo[3,2-b]pyrrole-4-carbonyl)-3-methyl-butyl]-4-[5-fluoro-2-(4-methyl-piperazin-1-yl)thiazol-4-yl]benzamide hydrate monohydrochloride, its use as a medicament and methods for its preparation.