The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

Dec. 12, 2014
Applicant:

Chong Kun Dang Pharmaceutical Corp., Seoul, KR;

Inventors:

Changsik Lee, Gyeonggi-do, KR;

Hyun-Mo Yang, Gyeonggi-do, KR;

Changkon Lee, Gyeonggi-do, KR;

Miseon Bae, Gyeonggi-do, KR;

Soyoung Kim, Gyeonggi-do, KR;

Youngil Choi, Gyeonggi-do, KR;

Nina Ha, Gyeonggi-do, KR;

Jaekwang Lee, Gyeonggi-do, KR;

Jungtaek Oh, Gyeonggi-do, KR;

Hyeseung Song, Gyeonggi-do, KR;

Ilhyang Kim, Gyeonggi-do, KR;

Daekyu Choi, Gyeonggi-do, KR;

Jaeki Min, Gyeonggi-do, KR;

Hyojin Lim, Gyeonggi-do, KR;

Daekwon Bae, Gyeonggi-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01); A61K 31/437 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.


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