The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

May. 11, 2016
Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Sougato Boral, Irvine, CA (US);

Thomas C. Malone, Irvine, CA (US);

Shimiao Wang, Tustin, CA (US);

Sandhya Rao, Irvine, CA (US);

Rong Yang, Mission Viejo, CA (US);

Assignee:

ALLERGAN, INC., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); C07D 401/04 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 409/14 (2013.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01);
Abstract

This invention is directed to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R, R, R, Rand X are as defined herein. The compounds of Formula I are useful as receptor tyrosine kinase (RTK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders and metabolic diseases.


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