The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2017
Filed:
Jul. 25, 2007
Applicants:
Luigi Bolondi, Bologna, IT;
Catia Giovannini, Bologna, IT;
Pásquale Chieco, San Lazzaro di Savena, IT;
Kenneth Marcu, Stony Brook, NY (US);
Inventors:
Luigi Bolondi, Bologna, IT;
Catia Giovannini, Bologna, IT;
Pásquale Chieco, San Lazzaro di Savena, IT;
Kenneth Marcu, Stony Brook, NY (US);
Assignee:
ALMA MATER STUDIORUM—UNIVERSITA' DI BOLOGNA, Bologna, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); A61K 31/704 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/704 (2013.01); C12N 15/1138 (2013.01); C12N 2310/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/53 (2013.01);
Abstract
The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.