The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

Jan. 20, 2005
Applicants:

Jochen Buck, Greenwich, CT (US);

Lonny R. Levin, New York, NY (US);

Fritz A. Muhlschlegel, Canterbury, GB;

Inventors:

Jochen Buck, Greenwich, CT (US);

Lonny R. Levin, New York, NY (US);

Fritz A. Muhlschlegel, Canterbury, GB;

Assignees:

Cornell Research Foundation, Inc., Ithaca, NY (US);

Kent University, Canterbury, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); A61K 31/4184 (2006.01); C12Q 1/527 (2006.01);
U.S. Cl.
CPC ...
A61K 31/415 (2013.01); A61K 31/4184 (2013.01); C12Q 1/527 (2013.01); G01N 2333/988 (2013.01);
Abstract

The present invention relates to a method of treating a disorder mediated by soluble adenylyl cyclase in a subject. The method involves administering to a subject an effective amount of a compound disclosed herein that modulates soluble adenylyl cyclase, under conditions effective to treat the disorder mediated by soluble adenylyl cyclase. The present invention also relates to a method of treating a disorder mediated by soluble adenylyl cyclase in a subject, where the disorder is selected from the group consisting of: learning or memory disorders, malaria, fungal infection, spinal cord injury, Alzheimer's disease, amyotrophic lateral sclerosis, and peripheral neuropathy. The method involves modulating soluble adenylyl cyclase in the subject. Another aspect of the present invention relates to a method of modulating soluble adenylyl cyclase. The method involves contacting eukaryotic cells with a compound that modulates soluble adenylyl cyclase, under conditions effective to modulate soluble adenylyl cyclase.


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