The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2017

Filed:

Dec. 16, 2014
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Tokitae Llc, Bellevue, WA (US);

Inventors:

Ana Jaklenec, Cambridge, MA (US);

Xian Xu, Waltham, MA (US);

Lowell L. Wood, Jr., Bellevue, WA (US);

Philip A. Eckhoff, Kirkland, WA (US);

William Gates, Redmond, WA (US);

Boris Nikolic, Seattle, WA (US);

Robert S. Langer, Newtown, MA (US);

Assignees:

Massachusetts Institute of Technology, Cambridge, MA (US);

Tokitae LLC, Bellevue, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A23L 1/304 (2006.01); A23L 1/00 (2006.01); A61K 47/00 (2006.01); A61K 9/50 (2006.01); A61K 31/519 (2006.01); A61K 47/26 (2006.01); A61K 47/36 (2006.01); A61K 31/295 (2006.01); A61K 33/30 (2006.01); A61K 31/07 (2006.01); A61K 31/714 (2006.01); A61K 31/375 (2006.01); A61K 31/593 (2006.01); A61K 33/18 (2006.01); A23P 10/30 (2016.01); A23L 27/00 (2016.01); A23L 33/10 (2016.01); A23L 33/15 (2016.01); A23L 33/155 (2016.01); A23L 33/16 (2016.01);
U.S. Cl.
CPC ...
A61K 9/5073 (2013.01); A23L 27/72 (2016.08); A23L 27/74 (2016.08); A23L 33/10 (2016.08); A23L 33/15 (2016.08); A23L 33/155 (2016.08); A23L 33/16 (2016.08); A23P 10/30 (2016.08); A61K 9/501 (2013.01); A61K 9/5026 (2013.01); A61K 31/07 (2013.01); A61K 31/295 (2013.01); A61K 31/375 (2013.01); A61K 31/519 (2013.01); A61K 31/593 (2013.01); A61K 31/714 (2013.01); A61K 33/18 (2013.01); A61K 33/30 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A23V 2002/00 (2013.01);
Abstract

Salt formulations, which are resistant to moisture and cooking conditions, are described herein. The formulations provide particles of micronutrients and vitamins encapsulated within heat resistant pH-sensitive water-insoluble polymers, which are packaged within a salt shell. The pH-sensitive, water-insoluble, thermally stable materials stabilize the micronutrients, particularly at high temperatures, such as during food preparation and cooking, and release the micronutrients at the desired locations such as the stomach, small intestine, etc. Preferred pH-sensitive polymers release at a low pH, less than the pH present in the stomach. The particles can be used to deliver daily-recommended doses of micronutrients simultaneously with salt, eliminating the need for vitamin pills. This is particularly important in populations suffering from severe malnutrition.


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