The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2017
Filed:
Jul. 25, 2012
Oliver J. Schmitz, Wuppertal, DE;
Volker Wulf, Langenfeld, DE;
Lukas Hyzak, Wuppertal, DE;
Michaela Wirtz, Wuppertal, DE;
David Melchior, Bergisch Gladbach, DE;
Hans Willi Kling, Wuppertal, DE;
Siegmar Gäb, Wuppertal, DE;
Ursula Gäb, Cologne, DE;
Oliver J. Schmitz, Wuppertal, DE;
Volker Wulf, Langenfeld, DE;
Lukas Hyzak, Wuppertal, DE;
Michaela Wirtz, Wuppertal, DE;
David Melchior, Bergisch Gladbach, DE;
Hans Willi Kling, Wuppertal, DE;
Siegmar Gäb, Wuppertal, DE;
Other;
Abstract
The present invention is concerned with a method of preparing a MALDI sample, the method comprising the steps of: (a) mixing a solid sample precursor comprising sample and matrix to form a solid sample mixture; (b) applying the solid sample mixture to a sample cavity of a MALDI target; and (c) compressing the solid sample mixture in the sample cavity so as to form a MALDI sample surface for laser desorption. The present invention also provides a MALDI target comprising a sample cavity for receiving a MALDI sample, the sample cavity having (a) a desorption end portion comprising an aperture, such that a portion of the MALDI sample exposed at the aperture is in use subjected to laser desorption; and wherein the sample cavity also has (b) a compression end portion adapted to permit compression of a solid sample mixture towards the desorption end portion in the sample cavity by applying a compression force to the solid sample mixture via the compression end portion.