The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2017
Filed:
Aug. 18, 2014
Jianfeng Cai, Tampa, FL (US);
Chuanhai Cao, Temple Terrace, FL (US);
Haifan Wu, Tampa, FL (US);
Yaqiong LI, Tampa, FL (US);
GE Bai, Tampa, FL (US);
Jianfeng Cai, Tampa, FL (US);
Chuanhai Cao, Temple Terrace, FL (US);
Haifan Wu, Tampa, FL (US);
Yaqiong Li, Tampa, FL (US);
Ge Bai, Tampa, FL (US);
UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);
Abstract
Embodiments of the present disclosure provide for γ-AApeptides, γ-AApeptide building blocks, methods of making γ-AApeptides and libraries of γ-AApeptides, methods of screening the γ-AApeptide libraries for desired peptidomimetic activity, and the like. The present disclosure also provides for γ-AApeptides that are inhibitors of Aβ peptide aggregation, methods of inhibiting and disassembling Aβ peptide aggregation, methods of inhibiting the toxicity of Aβ aggregates towards N2a neuroblasotma cells, as well as methods and compounds for treating Alzheimer's disease.