The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2017
Filed:
Aug. 27, 2014
Snu R&db Foundation, Seoul, KR;
Nano Intelligent Biomedical Engineering Corporation Co. Ltd., Chungcheongbuk-do, KR;
Yoon Jeong Park, Seoul, KR;
Gene Lee, Seoul, KR;
Hyun Nam, Seoul, KR;
Jin Sook Suh, Seoul, KR;
Chong-Pyoung Chung, Seoul, KR;
Jue-Yeon Lee, Gyeonggi-do, KR;
SNU R&DB FOUNDATION, Seoul, KR;
NANO INTELLIGENT BIOMEDICAL ENGINEERING CORPORATION CO. LTD., Chungcheongbuk-Do, KR;
Abstract
A method of preparing a reprogramming induced pluripotent stem cell from a human-derived somatic cell using a fusion protein in which a reprogramming inducing factor and cell permeable peptide (CPP) are fused, and a fusion protein in which a reprogramming inducing factor and a cell permeable peptide are fused are disclosed. According to the present invention, the induced pluripotent stem cell having high efficiency and high stability can be prepared by maximizing the effect of the reprogramming inducing transcription factor beyond the existing viral peptide transporter, in inducing the reprogramming of the somatic cell.