The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2017

Filed:

Jul. 12, 2013
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Young-Tae Kim, Arlington, TX (US);

Sreevidhya Banda, Arlington, TX (US);

Deepika Tamuly, Arlington, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0068 (2013.01); C12M 25/14 (2013.01); C12N 2533/52 (2013.01); C12N 2533/54 (2013.01); C12N 2533/90 (2013.01);
Abstract

In one aspect, films that can serve as a model or mimic for the basal lamina are described herein. In some embodiments, a film described herein comprises a top surface and a bottom surface in facing opposition to the top surface, wherein the film is formed from Type I collagen and one or more additional extracellular matrix proteins. The additional extracellular matrix proteins, in some cases, comprise one or more of Type IV collagen, laminin, and fibronectin. Moreover, in some instances, the weight ratio of Type I collagen to the additional extracellular matrix proteins in the film is at least about 40:1.


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