The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2017

Filed:

Sep. 29, 2014
Applicant:

Ono Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Akiharu Ishida, Osaka, JP;

Takeshi Matsushita, Osaka, JP;

Tetsuya Sekiguchi, Osaka, JP;

Yasuyuki Okabe, Osaka, JP;

Tatsuya Komagata, Osaka, JP;

Takuya Nishio, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 498/04 (2006.01); A61K 31/5383 (2006.01); A61K 45/06 (2006.01); A61K 31/4545 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/4545 (2013.01); A61K 31/5383 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention provides a somatostatin receptor subtype 2 agonist. A disclosed compound represented by the general formula (I): wherein all symbols have the same definitions as described in the specification;a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug of the foregoing is a low-molecular compound having strong somatostatin receptor subtype 2 agonistic activity, and thus can be administered in a simple manner, has high stability and has low toxicity. Therefore, the present compound is useful for prophylaxis and/or therapy of somatostatin-related diseases such as acromegaly and gastrointestinal obstruction.


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