The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2017

Filed:

Aug. 30, 2013
Applicant:

Ono Pharmaceutical Co., Ltd., Osaka-shi, Osaka, JP;

Inventors:

Kousuke Tani, Osaka, JP;

Akihiro Kinoshita, Osaka, JP;

Keisuke Hanada, Osaka, JP;

Yoshiyuki Aratani, Sakai, JP;

Takahiro Nekado, Osaka, JP;

Atsushi Shimabukuro, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/56 (2006.01); A61K 47/40 (2006.01); C07D 277/20 (2006.01); C07D 211/22 (2006.01); A61K 31/426 (2006.01); C08B 37/16 (2006.01); C08L 5/16 (2006.01);
U.S. Cl.
CPC ...
C07D 277/56 (2013.01); A61K 31/426 (2013.01); A61K 47/40 (2013.01); C07D 211/22 (2013.01); C07D 277/20 (2013.01); C08B 37/0015 (2013.01); C08L 5/16 (2013.01); C07B 2200/13 (2013.01);
Abstract

A compound that can be a therapeutic agent for underactive bladder which has low risk of side effects and can be administered orally is provided. Furthermore, a crystal which is advantageous in view of the stability, long-term storage, handleability, easiness of the drug preparation or the like as a drug substance of medicaments is provided. Since a salt of 2-[(2-{(1R,5R)-2-oxo-5-[(1E,4S)-7,8,8-trifluoro-4-hydroxy-4-methyl-1,7-octadien-1-yl]cyclopentyl}ethyl)thio]-1,3-thiazole-4-carboxylic acid or a diastereomeric mixture thereof and 4-piperidinemethanol is a chemically very stable crystal, it can be stored for a long time, and is very useful as a drug substance of medicaments.


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