The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2017
Filed:
Feb. 16, 2015
Jiangsu Nhwaluokang Pharmceutical Research and Development Co., Ltd, Xuzhou, Jiangsu, CN;
Qingeng Li, Chongqing, CN;
Tao Wang, Chongqing, CN;
Tong Wu, Chongqing, CN;
Lingguo Zeng, Chongqing, CN;
Yuanzhong Wang, Chongqing, CN;
Wei Mao, Chongqing, CN;
Gang Chen, Chongqing, CN;
Abstract
The present invention discloses a class of water-soluble propofol derivatives, preparation method thereof, anesthetization method using the same, use thereof as prodrugs and use thereof in the preparation of intravenous anesthetics. The water-soluble propofol derivatives have the general formula (I); wherein X is H or F, Y is F or alkyl substituted by one or more F, n is 1, 2, 3, 4, 5 or 6, W is Wor W; Wis NRR.A or Rand Rare each independently H, alkyl optionally substituted with phenyl, or cycloalkyl, m is 0, 1, 2 or 3, A is a pharmaceutically acceptable acid, Wis COOMor OPO(M)or PO(M); M is a metal ion, an ammonium ion or a basic amino acid cation which can form a salt with an acid radical; t is the charge number of M.