The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2017

Filed:

May. 24, 2011
Applicants:

Richard W. Andrews, Rehoboth, MA (US);

John Heden, Hollis, NH (US);

Michael Jackson, Woonsocket, RI (US);

John Lamoureux, Franklin, MA (US);

Guo-zhong LI, Westborough, MA (US);

Barry Sunray, Northborough, MA (US);

Thomas E. Wheat, Hopedale, MA (US);

Inventors:

Richard W. Andrews, Rehoboth, MA (US);

John Heden, Hollis, NH (US);

Michael Jackson, Woonsocket, RI (US);

John Lamoureux, Franklin, MA (US);

Guo-Zhong Li, Westborough, MA (US);

Barry Sunray, Northborough, MA (US);

Thomas E. Wheat, Hopedale, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01F 15/04 (2006.01); G05D 11/02 (2006.01); B01D 15/16 (2006.01); G01N 30/34 (2006.01);
U.S. Cl.
CPC ...
B01D 15/16 (2013.01); B01D 15/168 (2013.01); B01F 15/04 (2013.01); G01N 30/34 (2013.01); G05D 11/02 (2013.01);
Abstract

A method of preparing a liquid mixture for use in a liquid chromatography system is provided. The mixture comprises one or more acids, one or more bases, one or more salts, and one or more solvents, and the method comprises the steps of: i) calculating pH and/or salt concentration at a particular time t from a user-determined gradient function; and ii) based on the values obtained in step (i), calculating percent acid, percent base, percent salt and percent solvent in the liquid mixture at time t. A liquid chromatography system incorporating such method is also provided.


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