The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2017

Filed:

Jul. 16, 2015
Applicants:

Mohamad Elazizi, Weston, FL (US);

Peter Murray, Davie, FL (US);

H. Thomas Temple, Miami, FL (US);

Inventors:

Mohamad Elazizi, Weston, FL (US);

Peter Murray, Davie, FL (US);

H. Thomas Temple, Miami, FL (US);

Assignee:

Nova Southeastern University, Fort Lauderdale, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 5/00 (2006.01); A61P 19/00 (2006.01); A61P 29/00 (2006.01); A61L 27/54 (2006.01); A61L 27/18 (2006.01); A61L 27/26 (2006.01); A61L 27/24 (2006.01); A61L 27/22 (2006.01); A61L 27/10 (2006.01); A61L 27/36 (2006.01); A61L 27/12 (2006.01); A61F 2/28 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01);
U.S. Cl.
CPC ...
A61L 27/54 (2013.01); A61F 2/2846 (2013.01); A61L 27/10 (2013.01); A61L 27/12 (2013.01); A61L 27/18 (2013.01); A61L 27/225 (2013.01); A61L 27/24 (2013.01); A61L 27/26 (2013.01); A61L 27/365 (2013.01); A61L 27/3608 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61F 2002/2817 (2013.01); A61F 2002/2835 (2013.01); A61L 2430/02 (2013.01);
Abstract

The implantable scaffold matrix composition for osteogenic regeneration has a biodegradable polymer material selected from the group consisting of one or more of polylactic acid, polyglycolic acid, or polycaprolactone, or any combination thereof to provide a time release delivery of an osteogenic effect and further has a pharmaceutical composition selected from the group consisting of one or more of ibuprofen, non-steroidal anti-inflammatory drugs (NSAIDS), acetaminophen, or naproxen sodium or any combination thereof and wherein the implantable composition has a primary and a secondary time release. The primary time release being one of the polymer compositions; each time release extending occurring between 0 days and 19 days, both not being at 0 days. In a preferred composition, the scaffold has an organic material for inhibiting osteoclast selected from a group consisting of one or more of Galardin, Decorin, Actinonin, Marimastat, Batimastat, and phosphodiesterase type 4 or any combination of osteoclast inhibitors.


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