The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9642898 B1

PDF
Full Text
Expired
Date of Patent:
May. 09, 2017

Filed:

Nov. 21, 2014
Applicants:

Med Discovery S.a., Plan-les-Ouates, CH;

University of Zurich, Zurich, CH;

Inventors:

Adriano Fontana, Zurich, CH;

Mike Recher, Zurich, CH;

Christoph Kundig, Lausanne, CH;

Assignees:

MED DISCOVERY S.A., Cointrin/Geneva, CH;

UNIVERSITY OF ZURICH, Zurich, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/57 (2006.01); A61K 35/15 (2015.01); A61K 35/28 (2015.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/57 (2013.01); A61K 35/15 (2013.01); A61K 35/28 (2013.01); A61K 38/1709 (2013.01);
Abstract

The invention relates to therapeutic compounds which are inhibitors of serine proteases, to pharmaceutical compositions thereof and to their use in the treatment of the human or animal body. More specifically, the present invention relates to a method for the treatment of neutropenia comprising the administration to a subject in need thereof of a therapeutically effective amount of a serine protease inhibitor. The invention also comprises prevention of apoptosis of myeloid cells (1) during and after transfection of bone marrow cells performed for gene therapy, (2) during blood stem cell mobilization performed for reconstitution of hematopoiesis and (3) during infusion of cells of the myeloid lineage for reconstitution of hematopoiesis for gene therapy or for treatment of neutropenia by infusion of neutrophils.


Find Patent Forward Citations

Fontana, Adriano. (2017). Use of serine protease inhibitors in the treatment of neutropenia (U.S. Patent No. 9642898). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9642898

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…