The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2017
Filed:
Feb. 27, 2008
Elaine L. Jacobson, Tucson, AZ (US);
Myron K. Jacobson, Tucson, AZ (US);
Russell Coyle, Tucson, AZ (US);
Hyuntae Kim, Tucson, AZ (US);
Donna L. Coyle, Tucson, AZ (US);
Elaine L. Jacobson, Tucson, AZ (US);
Myron K. Jacobson, Tucson, AZ (US);
Russell Coyle, Tucson, AZ (US);
Hyuntae Kim, Tucson, AZ (US);
Donna L. Coyle, Tucson, AZ (US);
University of Kentucky Research Foundation, Lexington, KY (US);
Abstract
The invention relates to the use of nicotinic acid alkyl esters, especially myristyl nicotinate, to inhibit side effects associated with retinoic acid therapy. Also a part of the invention is a method for improving skin cell differentiation by administering the nicotinic acid alkyl ester in an amount sufficient to increase expression of caspase 14 and filaggrin. Deficiencies in expression of these molecules can be treated in this way as well.