The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2017
Filed:
Jun. 20, 2013
Institute of Radiation Medicine, China Academy of Military Medical Sciences Pla, Beijing, CN;
Xiaoming Yang, Beijing, CN;
Lin Wang, Beijing, CN;
Changyan Li, Beijing, CN;
Yiqun Zhan, Beijing, CN;
Jing Liu, Beijing, CN;
Teng Luo, Beijing, CN;
Haiyan Yan, Beijing, CN;
Shouguo Zhang, Beijing, CN;
Wei Li, Beijing, CN;
Xiaoxue Wen, Beijing, CN;
Tao Peng, Beijing, CN;
Lu Li, Beijing, CN;
Abstract
Disclosed in the present disclosure are substances having tyrosine kinase inhibitory activity and a preparation method and use thereof, wherein the substances are the compounds having the structure of general formula (I) or the geometric isomers or pharmaceutical salts thereof. Through evaluation on tyrosine kinase inhibitory activity and related experiments, the present disclosure demonstrates that these compounds have a good tyrosine kinase inhibitory activity, and may inhibit a variety of tumor cells, and thus may be developed into drugs for preventing and treating tumor diseases, especially liver cancer, lung cancer and neuroblastoma.