The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2017

Filed:

Jan. 31, 2014
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Vikas Gulani, Cleveland Heights, OH (US);

Yong Chen, Cleveland Heights, OH (US);

Nicole Seiberlich, Shaker Heights, OH (US);

Mark Griswold, Shaker Heights, OH (US);

Assignee:

Case Western Reserve University, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G08C 23/06 (2006.01); G01R 33/36 (2006.01); G01R 33/56 (2006.01); G01R 33/48 (2006.01); G01R 33/58 (2006.01); G01R 33/563 (2006.01); A61K 49/06 (2006.01); A61B 5/00 (2006.01); A61B 5/055 (2006.01);
U.S. Cl.
CPC ...
G08C 23/06 (2013.01); A61B 5/0017 (2013.01); A61B 5/0073 (2013.01); A61B 5/4244 (2013.01); A61K 49/06 (2013.01); G01R 33/3614 (2013.01); G01R 33/3692 (2013.01); G01R 33/4822 (2013.01); G01R 33/56 (2013.01); G01R 33/5608 (2013.01); G01R 33/56366 (2013.01); G01R 33/58 (2013.01); A61B 5/055 (2013.01);
Abstract

Example apparatus and methods provide improved spatial and temporal resolution over conventional magnetic resonance imaging (MRI) for a large (e.g., 500 cm) three dimensional (3D) volume. Example apparatus and methods reconstruct under-sampled 3D data associated with nuclear magnetic resonance (NMR) signals acquired from the volume using a 3D through-time non-Cartesian generalized auto-calibrating partially parallel acquisitions (GRAPPA) approach. The NMR signals are produced in response to a 3D non-Cartesian (e.g., stack-of-spirals) pulse sequence. Example apparatus and methods produce a quantified value for T1 relaxation, T2 relaxation, diffusion, or other NMR parameters in the volume from signal intensities in the data. The quantified value may describe, for example, a perfusion parameter, a blood flow parameter, a blood volume parameter, or other value. Greater precision is achieved for the NMR parameter in the volume as a result of the quantization performed on data acquired with greater spatial resolution and temporal resolution.


Find Patent Forward Citations

Loading…