The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2017
Filed:
May. 30, 2014
Genechem Inc., Daejeon, KR;
Jin Suk Woo, Daejeon, KR;
Byung-Gee Kim, Seoul, KR;
Dae Hee Kim, Daejeon, KR;
Yun Hee Choi, Seoul, KR;
Jae-Kyung Song, Chungcheongnam-do, KR;
Sun Youp Kang, Daejeon, KR;
Won Min Seo, Daejeon, KR;
Ji Young Yang, Daejeon, KR;
Sang Mi Lee, Daejeon, KR;
GENECHEM INC., Daejeon, KR;
Abstract
The present invention relates to a method for preparing a sialic acid derivative characterized by performing both of a process for preparing CMP-N-acetylneuraminic acid using N-acetyl-D-glucosamine and a process for preparing the sialic acid (neuraminic acid) derivative that combines a sialic acid with a galactose derivative or a lactose derivative, together, in one reactor. According to the method for preparing a sialic acid derivative of the present invention, expensive cytidine 5'-monophosphate (CMP) is capable of being recycled in a reactor, such that an amount of the CMP introduced into the reactor may be reduced, and the sialic acid derivative is capable of being prepared at a significantly high efficiency by using cheap N-acetyl-D-glucosamine, and pyruvate as substrates.