The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2017
Filed:
Aug. 20, 2014
Alisa K. Waterman, Weston, CT (US);
Nick Mark Devoogdt, Zemst, BE;
Tony Lahoutte, Ganshoren, BE;
Matthias Schneider, Bethel, CT (US);
Sanjaya Singh, Sandy Hook, CT (US);
Cedric Jozef Néotère Ververken, Merelbeke, BE;
Alisa K. Waterman, Weston, CT (US);
Nick Mark Devoogdt, Zemst, BE;
Tony Lahoutte, Ganshoren, BE;
Matthias Schneider, Bethel, CT (US);
Sanjaya Singh, Sandy Hook, CT (US);
Cedric Jozef Néotère Ververken, Merelbeke, BE;
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
The present invention relates to CX3CR1-targeting imaging agents and their use in treatment and diagnosis of diseases. Single domain CX3CR1-targeting polypeptides linked to detection labels and their use in in vivo imaging of atherosclerotic plaques are described. The CX3CR1-targeting imaging agents are useful in the treatment and diagnosis of CX3CR1-mediated diseases including atherosclerosis.