The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2017
Filed:
Dec. 18, 2013
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Christopher Dinsmore, Newton, MA (US);
Francesc Xavier Fradera Llinas, Brookline, MA (US);
Amit Ashokro Kudale, Singapore, SG;
Michelle Machacek, Brookline, MA (US);
Michael Hale Reutershan, Brighton, MA (US);
Christopher Francis Thompson, Arlington, MA (US);
B. Wesley Trotter, Medfield, MA (US);
Liping Yang, Arlington, MA (US);
Michael D. Altman, Needham, MA (US);
Stephane L. Bogen, Somerset, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Matthew E. Voss, Singapore, SG;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides substituted pyrrolopyrimidines of Formula I as described herein or a pharmaceutically acceptable salt or solvate thereof: The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.