The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2017

Filed:

Jun. 19, 2014
Applicant:

Syngenta Participations Ag, Basel, CH;

Inventors:

Raphael Dumeunier, Stein, CH;

Jilali Kessabi, Stein, CH;

Sebastian Volker Wendeborn, Stein, CH;

Hannes Nussbaumer, Stein, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/14 (2006.01); C07C 239/20 (2006.01);
U.S. Cl.
CPC ...
C07D 231/14 (2013.01); C07C 239/20 (2013.01);
Abstract

The present invention relates to a process for the enantioselective preparation of the compound of formula (Ib), which process comprises a) reducing the (E)- or (Z)-form of a compound of formula (II), with an enantioselective reagent to a compound of formula (IIIa), and b) acylating the compound of formula (IIIa) with the compound of formula (IV), or c) coupling the compound of formula (IV) with the compound of formula (II), to give a compound of formula (V) and d) reducing compound of formula (V) in the presence of hydrogen, a catalyst and a chiral ligand, to the compound of formula (Ib).


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