The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2017

Filed:

Jan. 05, 2015
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Jingwu Duan, Yardley, PA (US);

T. G. Murali Dhar, Newtown, PA (US);

Bin Jiang, Bryn Mawr, PA (US);

Ananta Karmakar, Bangalore, IN;

Arun Kumar Gupta, Bangalore, IN;

Zhonghui Lu, King of Prussia, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/54 (2006.01); C07D 309/08 (2006.01); C07D 401/06 (2006.01); C07D 405/06 (2006.01); C07D 211/96 (2006.01); A61K 31/352 (2006.01); A61K 31/4418 (2006.01);
U.S. Cl.
CPC ...
C07D 211/54 (2013.01); C07D 211/96 (2013.01); C07D 309/08 (2013.01); C07D 401/06 (2013.01); C07D 405/06 (2013.01);
Abstract

Described are RORγ modulators of the formula (I), [INSERT CHEMICAL STRUCTURE HERE] or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.


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