The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2017

Filed:

Apr. 15, 2016
Applicant:

Forma Therapeutics, Inc., Watertown, MA (US);

Inventors:

Pui Yee Ng, Waltham, MA (US);

Heather Davis, Haverhill, MA (US);

Kenneth W. Bair, Wellesley, MA (US);

Aleksandra Rudnitskaya, Roslindale, MA (US);

Xiaozhang Zheng, Lexington, MA (US);

Bingsong Han, North Haven, CT (US);

Nicholas Barczak, Waterford, CT (US);

David R. Lancia, Jr., Boston, MA (US);

Assignee:

Forma Therapeutics, Inc., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/96 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 417/06 (2006.01); C07D 491/107 (2006.01); C07D 413/06 (2006.01); C07D 405/06 (2006.01); C07D 471/04 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 405/04 (2006.01); C07D 405/10 (2006.01); C07D 221/20 (2006.01); C07D 497/10 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 209/96 (2013.01); C07D 221/20 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 405/10 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); C07D 491/107 (2013.01); C07D 497/10 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention is directed to inhibitors of histone deacetylases (HDACs) such as HDAC6 and HDAC11, and their use in the treatment of diseases such as cell proliferative diseases (e.g., cancer), neurological (e.g., neurodegenerative disease or neurodevelopmental disease), inflammatory or autoimmune disease, infection, metabolic disease, hematologic disease, or cardiovascular disease.


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