The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2017

Filed:

Jan. 13, 2015
Applicant:

Astellas Pharma Inc., Chuo-ku, Tokyo, JP;

Inventors:

Shunichiro Matsumoto, Tokyo, JP;

Takafumi Shimizu, Tokyo, JP;

Tomoyuki Saito, Tokyo, JP;

Takatoshi Kanayama, Tokyo, JP;

Hiroaki Tanaka, Tokyo, JP;

Chiharu Mori, Tokyo, JP;

Kazuhiro Yokoyama, Tokyo, JP;

Shigeo Matsui, Tokyo, JP;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/16 (2006.01); C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 209/16 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

[Problem] To provide a compound useful as a MTand/or MTreceptor agonist. [Solution] The present inventors have studied on MTand/or MTreceptor agonists, and have confirmed that indole compounds have the activity. As a result, the present invention is accomplished. That is, a compound represented by formula (I) or a salt thereof according to the present invention has a MTand/or MTreceptor agonistic activity and has a low ability of migrating into central nervous system. Therefore, the compound or a salt thereof can be used as a peripheral MTand/or MTreceptor agonist, and therefore can be used as a therapeutic and/or prophylactic agent for urinary incontinence, particularly stress urinary incontinence and mixed urinary incontinence.


Find Patent Forward Citations

Loading…