The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2017

Filed:

Mar. 14, 2014
Applicant:

Redhill Biopharma Ltd., Tel Aviv, IL;

Inventors:

Reza Fathi, HoHoKus, NJ (US);

Gilead Raday, Palo Alto, CA (US);

Assignee:

RedHill Biopharma Ltd., Tel Aviv, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/28 (2006.01); A61K 31/4178 (2006.01); A61K 9/24 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/286 (2013.01); A61K 9/209 (2013.01); A61K 9/2886 (2013.01); A61K 31/4178 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 9/2846 (2013.01);
Abstract

A solid oral dosage form includes a core comprising a non-ionic polymer matrix, a first amount of a first antiemetic drug or a pharmaceutically acceptable salt thereof dispersed within the matrix, and a salt dispersed within the matrix; a first seal coat of a non-ionic polymer matrix surrounding the core; and an immediate release drug layer surrounding the first seal coat, wherein the immediate release drug layer comprises a non-ionic polymer and a second amount of a second antiemetic drug or a pharmaceutically acceptable salt thereof dispersed therein, wherein the drug layer is sufficiently designed to release the second amount of the antiemetic drug over a period of at least 1 hour, wherein the solid oral dosage form is sufficiently designed to release the first amount of the first antiemetic drug and the second amount of the second antiemetic drug over a minimum period of 16 hours.


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