The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2017
Filed:
Jul. 26, 2016
Applicant:
Axolabs Gmbh, Kulmbach, DE;
Inventors:
Rainer Constien, Kulmbach, DE;
Anke Geick, Bayreuth, DE;
Philipp Hadwiger, Kulmbach, DE;
Torsten Haneke, Kulmbach, DE;
Ludger Ickenstein, Kulmbach, DE;
Carla Alexandra Hernandez Prata, Kulmbach, DE;
Andrea Schuster, Bayreuth, DE;
Timo Weide, Kulmbach, DE;
Assignee:
AXOLABS GMBH, Kulmbach, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 295/13 (2006.01); C07C 211/22 (2006.01); C07C 211/11 (2006.01); C07D 295/30 (2006.01); C07C 217/42 (2006.01); C07C 211/13 (2006.01); C07D 241/04 (2006.01); A61K 9/14 (2006.01); A61K 31/575 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); B82Y 5/00 (2011.01); C07C 211/14 (2006.01); C07C 217/08 (2006.01); C07C 217/28 (2006.01); A61K 9/127 (2006.01); A61K 31/70 (2006.01); A61K 38/02 (2006.01); A61K 47/22 (2006.01); A61K 39/00 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 9/145 (2013.01); A61K 9/1271 (2013.01); A61K 31/575 (2013.01); A61K 31/70 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/02 (2013.01); A61K 39/00 (2013.01); A61K 47/18 (2013.01); A61K 47/22 (2013.01); B82Y 5/00 (2013.01); C07C 211/11 (2013.01); C07C 211/13 (2013.01); C07C 211/14 (2013.01); C07C 211/22 (2013.01); C07C 217/08 (2013.01); C07C 217/28 (2013.01); C07C 217/42 (2013.01); C07D 241/04 (2013.01); C07D 295/13 (2013.01); C07D 295/30 (2013.01);
Abstract
The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.