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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9636298 B1

PDFFull Text
Expired
Date of Patent:
May. 02, 2017

Filed:

Jan. 15, 2015

Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs

Applicant:

Methylgene Inc., Montreal, CA;

Inventors:

Alain Ajamian, Montreal, CA;

Yves Andre Chantigny, Pincourt, CA;

Arkadii Vaisburg, Kirkland, CA;

Franck Raeppel, Montreal, CA;

Stephane Raeppel, St-Lazare, CA;

Robert Deziel, Mount-Royal, CA;

Assignee:

Other;

Attorney:

McDonnell Boehnen Hulbert & Berghoff LLP

Primary Examiner:

Samantha Shterengarts

Int. Cl.
CPC ...
C07D 207/16 (2006.01); C07D 211/60 (2006.01); C07C 259/06 (2006.01); C07C 271/60 (2006.01); C07C 275/16 (2006.01); C07C 309/15 (2006.01); C07D 239/557 (2006.01); C07D 241/08 (2006.01); C07D 263/22 (2006.01); C07D 205/04 (2006.01); C07D 273/08 (2006.01); C07D 211/34 (2006.01); C07D 211/44 (2006.01); C07D 211/58 (2006.01); C07D 211/62 (2006.01); A61K 31/223 (2006.01); A61K 31/40 (2006.01); A61K 31/661 (2006.01); A61K 31/495 (2006.01); A61K 31/5377 (2006.01); A61K 31/397 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 31/5375 (2006.01); C07D 309/12 (2006.01); C07D 295/185 (2006.01); C07D 295/192 (2006.01); C07D 295/205 (2006.01); C07F 9/09 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 31/223 (2013.01); A61K 31/397 (2013.01); A61K 31/40 (2013.01); A61K 31/495 (2013.01); A61K 31/5375 (2013.01); A61K 31/5377 (2013.01); A61K 31/661 (2013.01); A61K 45/06 (2013.01); C07C 259/06 (2013.01); C07C 271/60 (2013.01); C07C 275/16 (2013.01); C07C 309/15 (2013.01); C07D 205/04 (2013.01); C07D 207/16 (2013.01); C07D 211/34 (2013.01); C07D 211/44 (2013.01); C07D 211/58 (2013.01); C07D 211/60 (2013.01); C07D 211/62 (2013.01); C07D 239/557 (2013.01); C07D 241/08 (2013.01); C07D 263/22 (2013.01); C07D 273/08 (2013.01); C07D 295/185 (2013.01); C07D 295/192 (2013.01); C07D 295/205 (2013.01); C07D 309/12 (2013.01); C07F 9/091 (2013.01); C07C 2101/02 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01);
Abstract

The invention relates to prodrugs for use in the inhibition of histone deacetylase. The prodrugs of the present invention have good aqueous solubility and good aqueous stability. The prodrugs of the invention advantageously are metabolized to the active ingredient in plasma or in the blood stream of a warm-blooded animal. The invention also provides compositions and, and methods for making the prodrugs, and methods for using the prodrugs to treat fungal infections.

Find Patent Forward Citations

Ajamian, Alain. (2017). Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs (U.S. Patent No. 9636298). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9636298

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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