The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Nov. 12, 2014
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
The University of South Florida, Tampa, FL (US);
Anilkumar Harapanahalli Achyuta, Cambridge, MA (US);
Javier Cuevas, Lutz, FL (US);
Shivshankar Sundaram, Tampa, FL (US);
Chris Katnik, Wesley Chapel, FL (US);
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
The University of South Florida, Tampa, FL (US);
Abstract
This application provides devices for modeling ischemic stroke conditions. The devices can be used to culture neurons and to subject a first population of the neurons to low-oxygen conditions and a second population of neurons to normoxic conditions. The neurons are cultured on a porous barrier, and on the other side of the barrier run one or more fluid-filled channels. By flowing fluid with different oxygen levels through the channels, one can deliver desired oxygen concentrations to the cells nearest those channels.