The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9632033 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 25, 2017

Filed:

Jun. 22, 2015
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventors:

Venkat K. Balagurusamy, Suffern, NY (US);

Stephen J. Heisig, Tarrytown, NY (US);

Gong Su, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12M 1/34 (2006.01); C40B 40/06 (2006.01); G01N 21/75 (2006.01); G02B 21/36 (2006.01); G02B 21/00 (2006.01); G01N 21/64 (2006.01); G06K 9/00 (2006.01); G06T 7/20 (2017.01);
U.S. Cl.
CPC ...
G01N 21/75 (2013.01); G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G02B 21/0008 (2013.01); G02B 21/367 (2013.01); G06K 9/0014 (2013.01); G06T 7/204 (2013.01); G01N 2201/062 (2013.01); G01N 2201/0612 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/30072 (2013.01);
Abstract

A technique relates to determining a presence of a known nucleic acid sequence of a known molecule in a sample. A sample surface is coated with a select segment of the known molecule. Beads are coated with a first molecule. A targeted nucleic acid sequence is attached to a second molecule that binds to the first molecule, such that the targeted nucleic acid sequence is attached to the beads via first and second molecules. The sample is placed on the sample surface. The sample includes the liquid medium, beads, and targeted nucleic acid sequence being tested. Brownian motion of beads is monitored to determine whether the Brownian motion of the beads is restricted or not restricted. When the Brownian motion of beads is restricted, the presence of the known nucleic acid sequence is in the sample, thus indicating that the targeted nucleic acid sequence is the known nucleic acid sequence.


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