The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2017

Filed:

May. 14, 2016
Applicants:

International Business Machines Corporation, Armonk, NY (US);

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Daniel J. Coady, Bluffton, GA (US);

Richard A. Dipietro, Campbell, CA (US);

Amanda C. Engler, Woodbury, MN (US);

James L. Hedrick, Pleasanton, CA (US);

Victor W. L. Ng, Singapore, SG;

Zhan-Yuin Ong, London, GB;

Jeremy P. K. Tan, Singapore, SG;

Yi Yan Yang, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); C08G 63/64 (2006.01); A01N 33/12 (2006.01); A01N 43/50 (2006.01); A01N 57/34 (2006.01); A61K 9/00 (2006.01); A61K 31/765 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C08G 63/64 (2013.01); A01N 33/12 (2013.01); A01N 43/50 (2013.01); A01N 57/34 (2013.01); A61K 9/0019 (2013.01); A61K 31/765 (2013.01); A61K 47/481 (2013.01); A61K 47/48107 (2013.01); A61K 47/48123 (2013.01); A61K 2800/54 (2013.01); A61K 2800/542 (2013.01); A61K 2800/5426 (2013.01);
Abstract

Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.


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