The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Jul. 06, 2012
Jean Kadouche, Paris, FR;
Jean-pierre Mach, Bellevue, CH;
Olivier Michielin, Lausanne, CH;
Vincent Zoete, Morges, CH;
Justyna Iwaszkiewicz, Geneva, CH;
Martine Cerutti, Saint-christol-lez-ales, FR;
Sylvie Choblet, Ales, FR;
Josee Golay, Bergamo, IT;
Jean Kadouche, Paris, FR;
Jean-Pierre Mach, Bellevue, CH;
Olivier Michielin, Lausanne, CH;
Vincent Zoete, Morges, CH;
Justyna Iwaszkiewicz, Geneva, CH;
Martine Cerutti, Saint-christol-lez-ales, FR;
Sylvie Choblet, Ales, FR;
Josee Golay, Bergamo, IT;
Centre National de la Recherche Scientifique, Paris, FR;
Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, IT;
Universite de Lausanne, Lausanne, CH;
Abstract
The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy/light chain mispairing.