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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9630989 B1

PDFFull Text
Date of Patent:
Apr. 25, 2017

Filed:

Jul. 22, 2015

Dipeptide analogs for treating conditions associated with amyloid fibril formation

Applicant:

Ramot AT Tel-aviv University Ltd., Tel-Aviv, IL;

Inventors:

Ehud Gazit, Ramat-HaSharon, IL;

Yaniv Amir, Yahud, IL;

Ludmila Buzhansky, Ariel, IL;

Ulrich Abel, Bad Homburg, DE;

Anat Frydman-Marom, Tel-Aviv, IL;

Assignee:

Ramot at Tel-Aviv University Ltd., Tel-Aviv, IL;

Attorney:
Primary Examiner:

Christina Bradley

Assistant Examiner:

Zachary J Miknis

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 3/04 (2006.01); A61P 25/00 (2006.01); A61K 38/05 (2006.01); C07D 209/20 (2006.01); C07K 5/078 (2006.01);
U.S. Cl.
CPC ...
C07K 5/06156 (2013.01);
Abstract

Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The dipeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the dipetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.

Find Patent Forward Citations

Gazit, Ehud. (2017). Dipeptide analogs for treating conditions associated with amyloid fibril formation (U.S. Patent No. 9630989). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9630989

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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