The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Dec. 18, 2013
Neuroactive 19-alkoxy-17-substituted steroids, prodrugs thereof, and methods of treatment using same
Applicants:
Washington University, St. Louis, MO (US);
Sage Therapeutics, Inc., Cambridge, MA (US);
Inventors:
Douglas Covey, St. Louis, MO (US);
Albert Jean Robichaud, Ringoes, NJ (US);
Assignees:
Washington University, St. Louis, MO (US);
Sage Therapeutics, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07J 1/00 (2006.01); C07J 5/00 (2006.01); C07J 7/00 (2006.01); C07J 21/00 (2006.01); C07J 41/00 (2006.01); C07J 51/00 (2006.01);
U.S. Cl.
CPC ...
C07J 1/0029 (2013.01); C07J 1/0011 (2013.01); C07J 1/0018 (2013.01); C07J 5/0015 (2013.01); C07J 7/002 (2013.01); C07J 21/00 (2013.01); C07J 41/0005 (2013.01); C07J 41/0094 (2013.01); C07J 21/006 (2013.01); C07J 21/008 (2013.01); C07J 41/0016 (2013.01); C07J 51/00 (2013.01);
Abstract
The present disclosure is generally directed to neuroactive 19-alkoxy-17-substituted steroids as referenced herein, and pharmaceutically acceptable salts thereof, for use as, for example, an anesthetic, and/or in the treatment of disorders relating to GABA function and activity. The present disclosure is further directed to pharmaceutical compositions comprising such compounds.