The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Jul. 24, 2015
Applicant:
Epizyme, Inc., Cambridge, MA (US);
Inventors:
Richard Chesworth, Concord, MA (US);
Lorna Helen Mitchell, Cambridge, MA (US);
Gideon Shapiro, Gainesville, FL (US);
Oscar Miguel Moradei, Burlington, MA (US);
Assignee:
Epizyme, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 409/04 (2006.01); C07D 403/04 (2006.01); C07D 413/04 (2006.01); C07D 231/12 (2006.01); C07D 407/04 (2006.01); C07D 411/04 (2006.01); C07D 405/04 (2006.01); C07D 417/04 (2006.01); A61K 31/415 (2006.01); A61K 31/4155 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 31/42 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 31/42 (2013.01); A61K 31/428 (2013.01); A61K 31/437 (2013.01); C07D 231/12 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 407/04 (2013.01); C07D 409/04 (2013.01); C07D 411/04 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01);
Abstract
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.