The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Sep. 13, 2013
Peter B. Dervan, San Marino, CA (US);
Nicholas G. Nickols, Van Nuys, CA (US);
Claire S. Jacobs, Cambridge, MA (US);
Michelle E. Farkas, Amherst, MA (US);
Daniel A. Harki, Minneapolis, MN (US);
Peter B. Dervan, San Marino, CA (US);
Nicholas G. Nickols, Van Nuys, CA (US);
Claire S. Jacobs, Cambridge, MA (US);
Michelle E. Farkas, Amherst, MA (US);
Daniel A. Harki, Minneapolis, MN (US);
California Institute of Technology, Pasadena, CA (US);
Abstract
The present invention relates to polyamides capable of inhibiting ARE-, GRE- and ERE-mediated gene regulation in cells. The present invention also relates to polyamides capable of modulating the activity of RNA polymerase II and p53. The invention also relates to methods to treat diseases related to ARE-, GRE- and ERE-mediated gene regulation and to RNA polymerase II and p53 activity.