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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9630947 B1

PDFFull Text
Date of Patent:
Apr. 25, 2017

Filed:

Apr. 21, 2015

Therapeutic compounds and related methods of use

Applicant:

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Masaki Suzuki, Osaka, JP;

Kazumi Kondo, Osaka, JP;

Muneaki Kurimura, Osaka, JP;

Krishna Reddy Valluru, Hyderabad, IN;

Akira Takahashi, Osaka, JP;

Takeshi Kuroda, Osaka, JP;

Haruka Takahashi, Osaka, JP;

Tae Fukushima, Osaka, JP;

Shin Miyamura, Osaka, JP;

Indranath Ghosh, Olney, MD (US);

Abhishek Dogra, Somerville, MA (US);

Geraldine Harriman, Charlestown, RI (US);

Amy Elder, Arlington, MA (US);

Satoshi Shimizu, Osaka, JP;

Kevin J. Hodgetts, Framingham, MA (US);

Jason S. Newcom, Norfolk, MA (US);

Assignee:

OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;

Attorney:

Lando & Anastasi, LLP

Primary Examiner:

Jeffrey H Murray

Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/517 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01); C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract

Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP), such as those of formula (III), and composition thereof are described herein. Exemplary disorders include schizophrenia and cognitive deficit.

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