The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Aug. 13, 2015
Applicant:
Wyeth Llc, New York, NY (US);
Inventors:
Quinhong Lu, Suffern, NY (US);
Mannching Sherry Ku, Thiells, NY (US);
Warren Chew, Pierrefonds, CA;
Gloria Cheal, Beaconsfield, CA;
Anthony F. Hadfield, St. Petersburg, FL (US);
Mahmoud Mirmehrabi, Laval, CA;
Assignee:
WYETH LLC, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07C 51/41 (2006.01); C07C 57/145 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07C 51/412 (2013.01); C07C 57/145 (2013.01);
Abstract
The present invention relates to maleate salt forms of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide, methods of preparing crystalline maleate salt forms, the associated compounds, and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.