The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2017

Filed:

Dec. 17, 2013
Applicants:

Vikki Furminger, East Sussex, GB;

Owen Rhys Hughes, Derbyshire, GB;

Darren Mark Le Grand, East Grinstead, GB;

Emily Stanley, Horsham, GB;

Christopher Thomson, Belmont, MA (US);

Inventors:

Vikki Furminger, East Sussex, GB;

Owen Rhys Hughes, Derbyshire, GB;

Darren Mark Le Grand, East Grinstead, GB;

Emily Stanley, Horsham, GB;

Christopher Thomson, Belmont, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/454 (2006.01); C07D 451/04 (2006.01); A61K 31/4192 (2006.01); A61K 31/445 (2006.01); A61K 31/46 (2006.01); A61K 31/496 (2006.01); A61K 31/5375 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); C07D 211/32 (2006.01); C07D 211/60 (2006.01); C07D 249/04 (2006.01); C07D 265/30 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 401/06 (2006.01); C07D 263/38 (2006.01); C07D 211/26 (2006.01); C07D 211/34 (2006.01); C07D 211/58 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/4192 (2013.01); A61K 31/445 (2013.01); A61K 31/454 (2013.01); A61K 31/46 (2013.01); A61K 31/496 (2013.01); A61K 31/5375 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 211/26 (2013.01); C07D 211/32 (2013.01); C07D 211/34 (2013.01); C07D 211/58 (2013.01); C07D 211/60 (2013.01); C07D 249/04 (2013.01); C07D 263/38 (2013.01); C07D 265/30 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 451/04 (2013.01);
Abstract

The present invention relates to novel compounds of formula (I) (I) that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in the treatment of an ATX-dependent or ATX-mediated disease or condition.


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